Use of S. pombe to Characterize Mammalian Adenylyl Cyclases and Their Inhibitors

Thesis advisor: Charles Hoffman === The study of mammalian cAMP signaling has often been confounded by the fact that ten different genes encode adenylyl cyclases (ACs) that produce cAMP from ATP and 16 different genes encode phosphodiesterases (PDEs) that hydrolyze cAMP to AMP. In this study, mammal...

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Bibliographic Details
Main Author: Gottlieb, Rachel
Format: Others
Language:English
Published: Boston College 2015
Subjects:
Online Access:http://hdl.handle.net/2345/bc-ir:104220