S. cerevisiae Srs2 helicase ensures normal recombination intermediate metabolism during meiosis and prevents accumulation of Rad51 aggregates

S. cerevisiae Srs2 helicase ensures normal recombination intermediate metabolism during meiosis and prevents accumulation of Rad51 aggregates

Yes === We investigated the meiotic role of Srs2, a multi-functional DNA helicase/translocase that destabilises Rad51-DNA filaments and is thought to regulate strand invasion and prevent hyper-recombination during the mitotic cell cycle. We find that Srs2 activity is required for normal meiotic prog...

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Bibliographic Details
Main Authors: Hunt, L.J., Ahmed, E.A., Kaur, H., Ahuja, J.S., Hulme, L., Chou, T.C., Lichten, M., Goldman, Alastair S.H.
Language:en
Published: 2019
Subjects:
Budding yeast
Meiosis
Rad51
Recombination
Srs2 helicase
Online Access:http://hdl.handle.net/10454/17048

Internet

http://hdl.handle.net/10454/17048

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