GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions

GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions

Yes === Drug resistance diagnostics that rely on the detection of resistance-related mutations could expedite patient care and TB eradication. We perform minimum inhibitory concentration testing for 12 anti-TB drugs together with Illumina whole-genome sequencing on 1452 clinical Mycobacterium tuberc...

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Bibliographic Details
Main Authors: Farhat, M.R., Freschi, L., Calderon, R., Ioerger, T., Snyder, M., Meehan, Conor J., de Jong, B.C., Rigouts, L., Sloutsky, A., Kaur, D., Sunyaev, S., van Soolingen, D., Shendure, J., Sacchettini, J., Murray, M.
Language:en
Published: 2019
Subjects:
Antimicrobial resistance
Bacterial genetics
Genome-wide association studies
Tuberculosis
Online Access:http://hdl.handle.net/10454/17274

Internet

http://hdl.handle.net/10454/17274

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