Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression.

Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression.

Yes === Aneuploidy is usually deleterious in multicellular organisms but appears to be tolerated and potentially beneficial in unicellular organisms, including pathogens. Leishmania, a major protozoan parasite, is emerging as a new model for aneuploidy, since in vitro-cultivated strains are highly...

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Bibliographic Details
Main Authors: Dumetz, F., Imamura, H., Sanders, M., Seblova, V., Myskova, J., Pescher, P., Vanaerschot, M., Meehan, Conor J., Cuypers, B., De Muylder, G., Späth, G.F., Bussotti, G., Vermeesch, J.R., Berriman, M., Cotton, J.A., Volf, P., Dujardin, J.-C., Domagalska, M.A.
Language:en
Published: 2019
Subjects:
Leishmania
Aneuploidy
Gene dosage
Genomics
Life cycle
Online Access:http://hdl.handle.net/10454/17310

Internet

http://hdl.handle.net/10454/17310

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