Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice

Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice

Yes === O-GlcNAcylation is an abundant post-translational modification in the nervous system, linked to both neurodevelopmental and neurodegenerative disease. However, the mechanistic links between these phenotypes and site-specific O-GlcNAcylation remain largely unexplored. Here, we show that Ser51...

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Bibliographic Details
Main Authors: Muha, V., Williamson, Ritchie, Hills, R., McNeilly, A.D., McWilliams, T.G., Alonso, J., Schimpl, M., Leney, A.C., Heck, A.J.R., Sutherland, C., Read, K.D., McCrimmon, R.J., Brooks, S.P., van Aalten, D.M.F.
Language:en
Published: 2019
Subjects:
O-GlcNAcylation
CRMP2
Cross talk
Cognitive function
Online Access:http://hdl.handle.net/10454/17525

Internet

http://hdl.handle.net/10454/17525

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