Comparative genomics of Mycobacterium africanum Lineage 5 and Lineage 6 from Ghana suggests distinct ecological niches

Yes === Mycobacterium africanum (Maf) causes a substantial proportion of human tuberculosis in some countries of West Africa, but little is known on this pathogen. We compared the genomes of 253 Maf clinical isolates from Ghana, including N = 175 Lineage 5 (L5) and N = 78 Lineage 6 (L6). We found th...

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Main Authors: Otchere, I.D., Coscollá, M., Sánchez-Busó, L., Asante-Poku, A., Brites, D., Loiseau, C., Meehan, Conor J., Osei-Wusu, S., Forson, A., Laryea, C., Yahayah, A.I., Baddoo, A., Ansa, G.A., Aboagye, S.Y., Asare, P., Borrell, S., Gehre, F., Beckert, P., Kohl, T.A., N'dira, S., Beisel, C., Antonio, M., Niemann, S., de Jong, B.C., Parkhill, J., Harris, S.R., Gagneux, S., Yeboah-Manu, D.
Language:en
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10454/17572