Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumour drug accumulation and limiting bioavailability and toxicity in normal tissues

Yes === Most cancer patients receive chemotherapy at some stage of their treatment which makes improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large numbers of potent anti-cancer agents being developed, a major obstacle to clinical translation remains the inability t...

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Bibliographic Details
Main Authors: Ingram, N., McVeigh, L.E., Abou-Saleh, R.H., Maynard, J., Peyman, S.A., McLaughlan, J.R., Fairclough, M., Marston, G., Valleley, E.M.A., Jimenez-Macias, J.L., Charalambous, A., Townley, W., Haddrick, M., Wierzbicki, A., Wright, A., Volpato, M., Simpson, P.B., Treanor, D.E., Thomson, N.H., Loadman, Paul M., Bushby, R.J., Johnson, B.R.G., Jones, P.F., Evans, T., Freear, S., Markham, A.F., Evans, S.D., Coletta, P.L.
Language:en
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10454/17999