Nucleosides Rescue Replication-Mediated Genome Instability of Human Pluripotent Stem Cells
Yes === Human pluripotent stem cells (PSCs) are subject to the appearance of recurrent genetic variants on prolonged culture. We have now found that, compared with isogenic differentiated cells, PSCs exhibit evidence of considerably more DNA damage during the S phase of the cell cycle, apparently as...
Main Authors: | , , , , , , , , , , |
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Language: | en |
Published: |
2020
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Subjects: | |
Online Access: | http://hdl.handle.net/10454/18013 |