Injection moulded controlled release amorphous solid dispersions: Synchronized drug and polymer release for robust performance

Injection moulded controlled release amorphous solid dispersions: Synchronized drug and polymer release for robust performance

Yes === A study has been carried out to investigate controlled release performance of caplet shaped injection moulded (IM) amorphous solid dispersion (ASD) tablets based on the model drug AZD0837 and polyethylene oxide (PEO). The physical/chemical storage stability and release robustness of the IM t...

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Bibliographic Details
Main Authors: Deshmukh, Shivprasad S., Paradkar, Anant R., Abrahmsén-Alami, S., Govender, R., Viridén, A., Winge, F., Matic, H., Booth, J., Kelly, Adrian L.
Language:en
Published: 2020
Subjects:
Oral solid dosage (OSD)
Polymer release
Release robustness
Poorly soluble drug
Polyethylene oxide (PEO)
Hot melt extrusion (HME)
Injection moulding (IM)
Controlled release
Amorphous solid dispersion (ASD)
Online Access:http://hdl.handle.net/10454/18155

Internet

http://hdl.handle.net/10454/18155

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