Progress towards a clinically-successful ATR inhibitor for cancer therapy
Yes === The DNA damage response (DDR) is now known to play an important role in both cancer development and its treatment. Targeting proteins such as ATR (Ataxia telangiectasia mutated and Rad3-related) kinase, a major regulator of DDR, has demonstrated significant therapeutic potential in cancer tr...
Main Authors: | Barnieh, Francis M., Loadman, Paul M., Falconer, Robert A. |
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Language: | en |
Published: |
2021
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Subjects: | |
Online Access: | http://hdl.handle.net/10454/18345 |
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