Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, Combretastatin A4

Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, Combretastatin A4

Yes === The hydrophobicity of a drug can be a major challenge in its development and prevents the clinical translation of highly potent anti-cancer agents. We have used a lipid-based nanoemulsion termed Lipid-Oil-Nanodroplets (LONDs) for the encapsulation and in vivo delivery of the poorly bioavaila...

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Bibliographic Details
Main Authors: Charalambous, A., Mico, V., McVeigh, L.E., Marston, G., Ingram, N., Volpato, M., Peyman, S.A., McLaughlan, J.R., Wierzbicki, Antonia, Loadman, Paul M., Bushby, R.J., Markham, A.F., Evans, S.D., Coletta, P.L.
Language:en
Published: 2021
Subjects:
Lipid-Oil-Nanodroplets (LONDs)
Combretastatin A4
Microbubbles
Targeting
Ultrasound trigger
Online Access:http://hdl.handle.net/10454/18516

Internet

http://hdl.handle.net/10454/18516

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