Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains

Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains

no === The role of mutations in genes associated with phenotypic resistance to bedaquiline (BDQ) and delamanid (DLM) in Mycobacterium tuberculosis complex (MTBc) strains is poorly characterized. A clear understanding of the genetic variants' role is crucial to guide the development of molecular...

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Bibliographic Details
Main Authors: Battaglia, S., Spitaleri, A., Cabibbe, A.M., Meehan, Conor J., Utpatel, C., Ismail, N., Tahseen, S., Skrahina, A., Alikhanova, N., Mostofa Kamal, S.M., Barbova, A., Niemann, S., Groenheit, R., Dean, A.S., Zignol, M., Rigouts, L., Cirillo, D.M.
Language:en
Published: 2021
Subjects:
Bedaquiline
Delamanid
Mycobacterium tuberculosis
New drug resistance
Whole-genome sequencing
Online Access:http://hdl.handle.net/10454/18532

Internet

http://hdl.handle.net/10454/18532

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