A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes.

No === The proopiomelanocortin (POMC)-derived peptides, ACTH and alpha-MSH, are the principal mediators of human skin pigmentation via their action at the melanocortin-1 receptor (MC-1R). Recent data have demonstrated the existence of a functionally active beta-endorphin/mu-opiate receptor system in...

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Bibliographic Details
Main Authors: Kauser, Sobia, Thody, Anthony J., Schallreuter, Karin U., Gummer, C.L., Tobin, Desmond J.
Language:en
Published: 2009
Subjects:
MSH
Online Access:http://hdl.handle.net/10454/3456