Melanosomal pH controls rate of melanogenesis, eumelanin/phaeomelanin ratio and melanosome maturation in melanocytes and melanoma cells.

No === The skin pigment melanin is produced in melanocytes in highly specialized organelles known as melanosomes. Melanosomes are related to the organelles of the endosomal/lysosomal pathway and can have a low internal pH. In the present study we have shown that melanin synthesis in human pigment ce...

Full description

Bibliographic Details
Main Authors: Ancans, Janis, Tobin, Desmond J., Hoogduijn, Martin J., Smit, N.P., Wakamatsu, K., Thody, Anthony J.
Language:en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10454/3681