Neuromedin U can exert colon-specific, enteric nerve-mediated prokinetic activity, via a pathway involving NMU1 receptor activation.

No === The neuromedin U (NMU) receptors, NMU1 and NMU2, are expressed in the gut but their functions are unclear. This study explores the role of NMU in gastrointestinal motility. Experimental approach: The effects of NMU were examined in the forestomach and colon isolated from NMU2R wild-type a...

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Bibliographic Details
Main Authors: Dass, N.B., Bassil, A.K., North-Laidler, V.J., Morrow, R., Aziz, E., Tuladhar, Bishwa R., Sanger, G.J.
Language:en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10454/3756