Genomewide expression profiling of the cryptolepine-induced toxicity in Saccharomyces cerevisiae.

no === We have used the budding yeast Saccharomyces cerevisiae to identify genes that may confer sensitivity in vivo to the antimalarial and cytotoxic agent cryptolepine. Five S. cerevisiae strains, with different genetic backgrounds in cell permeability and DNA damage repair mechanisms, were expo...

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Bibliographic Details
Main Authors: Rojas, M., Wright, Colin W., Pina, B., Portugal, J.
Language:en
Published: American Chemical Society 2010
Subjects:
Online Access:http://hdl.handle.net/10454/4531