Role of inhibition of protein prenylation in the cholesterol-dependent and cholesterol-independent effects of simvastatin
Statins are widely used to treat hypercholesterolemia. Statins inhibit cholesterol biosynthesis, thereby activating genes involved in cholesterol homeostasis, which are under the control of the Sterol Regulatory Element (SRE). Statins also have cholesterol-independent beneficial cardiovascular effec...
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| Format: | Others |
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2011
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| Online Access: | http://cardinalscholar.bsu.edu/handle/handle/188222 http://liblink.bsu.edu/uhtbin/catkey/1339597 |