Does the apoptotic activity of cells ectopically expressing TAL1 and LMO1 revert to normal after RNA interference induced silencing of TAL1 and LMO1?
T-cell acute lymphoblastic leukemia (T-ALL) is a childhood cancer created through genetic alterations; most commonly upregulation of TALI and LMOI oncoproteins. T-ALL is treated with radiation and chemotherapy, but malignant T-cells are resistant to apoptotic stimulation. To study this disorder, AKR...
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| Format: | Others |
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2011
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| Online Access: | http://cardinalscholar.bsu.edu/handle/handle/188453 http://liblink.bsu.edu/uhtbin/catkey/1398711 |