Approach to the Synthesis of Chlorothricolide: Synthesis of (±)-19,20-Dihydro-24-O-methylchlorotricolide, methyl ester, ethyl carbonate

Approach to the Synthesis of Chlorothricolide: Synthesis of (±)-19,20-Dihydro-24-O-methylchlorotricolide, methyl ester, ethyl carbonate

<p>An approach to the total synthesis of the 14-membered macrolide antibiotic aglycon chlorothricolide is presented. Key steps from the two halves to (±)-19,20-Dihydro-24-O methylchlorothricolide, methyl ester, ethyl carbonate include initial esterification across the C1 and C25 carbons follow...

Full description

Bibliographic Details
Main Author: Varney, Michael David
Format: Others
Language:en
Published: 1986
Online Access:https://thesis.library.caltech.edu/11412/1/Varney_MD_1986.pdf
Varney, Michael David (1986) Approach to the Synthesis of Chlorothricolide: Synthesis of (±)-19,20-Dihydro-24-O-methylchlorotricolide, methyl ester, ethyl carbonate. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/h9ke-rp15. https://resolver.caltech.edu/CaltechTHESIS:02272019-121930852 <https://resolver.caltech.edu/CaltechTHESIS:02272019-121930852>

Internet

https://thesis.library.caltech.edu/11412/1/Varney_MD_1986.pdf
Varney, Michael David (1986) Approach to the Synthesis of Chlorothricolide: Synthesis of (±)-19,20-Dihydro-24-O-methylchlorotricolide, methyl ester, ethyl carbonate. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/h9ke-rp15. https://resolver.caltech.edu/CaltechTHESIS:02272019-121930852 <https://resolver.caltech.edu/CaltechTHESIS:02272019-121930852>

Similar Items