Full Sequence Design of an Alpha-Helical Protein and Investigation of the Importance of Helix Dipole and Capping Effects in Helical Protein Design
<p>Our goal is an objective, quantitative design algorithm based on the physical chemical forces which determine protein structure and stability. To this end, we have developed a cyclical protein design strategy which utilizes theory, computation, and experimentation using a variety of prot...
Internet
https://thesis.library.caltech.edu/11451/1/Morgan_CS_2000.pdfMorgan, Chantal Smith (2000) Full Sequence Design of an Alpha-Helical Protein and Investigation of the Importance of Helix Dipole and Capping Effects in Helical Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8wn3-cv27. https://resolver.caltech.edu/CaltechTHESIS:04092019-114920250 <https://resolver.caltech.edu/CaltechTHESIS:04092019-114920250>