Binding site size limitations of imidazole-pyrrole polyamides for recognition in the minor groove of DNA

Binding site size limitations of imidazole-pyrrole polyamides for recognition in the minor groove of DNA

<p>The discovery that the three ring polyamide Im-Py-Py-Dp containing imidazole (Im) and pyrrole (Py) carboxamides binds the DNA sequence 5'-(A,T)G(A,T)C(A,T)-3' as an antiparallel dimer offers a new model for the design of ligands for specific recognition of sequences in the mino...

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Bibliographic Details
Main Author: Kelly, James J.
Format: Others
Language:en
Published: 1996
Online Access:https://thesis.library.caltech.edu/8124/2/Kelly_jj_1996.pdf
Kelly, James J. (1996) Binding site size limitations of imidazole-pyrrole polyamides for recognition in the minor groove of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/jc2t-pr07. https://resolver.caltech.edu/CaltechTHESIS:03112014-150124711 <https://resolver.caltech.edu/CaltechTHESIS:03112014-150124711>

Internet

https://thesis.library.caltech.edu/8124/2/Kelly_jj_1996.pdf
Kelly, James J. (1996) Binding site size limitations of imidazole-pyrrole polyamides for recognition in the minor groove of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/jc2t-pr07. https://resolver.caltech.edu/CaltechTHESIS:03112014-150124711 <https://resolver.caltech.edu/CaltechTHESIS:03112014-150124711>

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