Lynxl and the β2V287L Mutation Affect the Stoichiometry of the α4β2 Nicotinic Acetylcholine Receptor
GPI-anchored neurotoxin-like receptor binding proteins, such as lynx modulators, are topologically positioned to exert pharmacological effects by binding to the extracellular portion of nAChRs. These actions are generally thought to proceed when both lynx and the nAChRs are on the plasma membrane. H...
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https://thesis.library.caltech.edu/8430/1/2014-5-27%20Weston%20Nichols%20Caltech%20Thesis%20Final.pdfNichols, Weston A. (2014) Lynxl and the β2V287L Mutation Affect the Stoichiometry of the α4β2 Nicotinic Acetylcholine Receptor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2S9B-R910. https://resolver.caltech.edu/CaltechTHESIS:05292014-190146869 <https://resolver.caltech.edu/CaltechTHESIS:05292014-190146869>