Biochemical and Biophysical Characterization of Huntingtin
<p>Huntington’s disease (HD) is a fatal autosomal dominant neurodegenerative disease. HD has no cure, and patients pass away 10-20 years after the onset of symptoms. The causal mutation for HD is a trinucleotide repeat expansion in exon 1 of the huntingtin gene that leads to a polyglutamine (p...
Internet
https://thesis.library.caltech.edu/9270/7/Owens_PhD_Thesis.pdfOwens, Gwen Ellen (2016) Biochemical and Biophysical Characterization of Huntingtin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9TM7835. https://resolver.caltech.edu/CaltechTHESIS:11042015-142900908 <https://resolver.caltech.edu/CaltechTHESIS:11042015-142900908>