The study of susceptibility and resistance of HIV integrases to integrase strand transfer inhibitors and the development of novel single domain antibody targeting HIV integrase
This thesis presents the determination of susceptibility and resistance of HIV integrases (INs) to IN strand transfer inhibitors (INSTIs) and the development of single domain antibody (sdAb) targeting HIV IN. Firstly, the susceptibility of HIV-1 subtype CRF02_AG INs to the latest INSTIs was determin...
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| Language: | ENG |
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École normale supérieure de Cachan - ENS Cachan
2011
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| Online Access: | http://tel.archives-ouvertes.fr/tel-00654080 http://tel.archives-ouvertes.fr/docs/00/65/40/80/PDF/Ni2011.pdf |