Progesterone Receptor Isoforms : functional Selectivity and Pharmacological Targeting
Progesterone receptor (PR) is an essential pharmacological target for contraception, female reproductive disorders as well as for hormone-dependent breast and uterine cancers. Human PR is expressed as two major isoforms PRA and PRB which behave as distinct transcriptional factors. PRA vs PRB express...
Main Author: | |
---|---|
Language: | English |
Published: |
Université Paris Sud - Paris XI
2011
|
Subjects: | |
Online Access: | http://tel.archives-ouvertes.fr/tel-00769945 http://tel.archives-ouvertes.fr/docs/00/76/99/45/PDF/VA_KHAN_JUNAID_-_ALI_06102011.pdf |