Design, synthesis and biological evaluation of new platelet aggregation inhibitors and novel methodologies for the preparation of CF₂R containing molecules
The first part of the thesis deals with the synthesis and biological evaluation of new platelets aggregation inhibitors, based on 12-HETE, 13-HODE and their analogues. In the second part we are interested in novel methodologies for the preparation of CF₂-containing molecules : First, a flexible stra...
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| Language: | ENG |
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Université Rennes 1
2013
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| Online Access: | http://tel.archives-ouvertes.fr/tel-00861475 http://tel.archives-ouvertes.fr/docs/00/86/14/75/PDF/KHALAF_Ali.pdf |