Effect of O-GlcNAcylation on tamoxifen sensitivity in breast cancer derived MCF-7 cells
One of the hallmarks of cancer cells is to exhibit increased uptake and consumption of glucose.3-5% of the glucose entering into the cell leads to a minor pathway of the glucose metabolismknown as the hexosamine biosynthetic pathway (HBP). UDP-N-acetylglucosamine is the endproduct of HBP and is used...
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| Language: | ENG |
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Université René Descartes - Paris V
2013
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| Online Access: | http://tel.archives-ouvertes.fr/tel-00912341 http://tel.archives-ouvertes.fr/docs/00/91/23/41/PDF/va_Kanwal_Shahzina.pdf |