Studying the posttranslational modifications of transcription factor Ikaros and their role in its function

The main topic of my PhD studies was to investigate the role of sumoylation in the function of Ikaros transcription factor, that regulates the lymphocyte differentiation and function. Sumoylation is a posttranslational modification that can change the properties and regulate the function of a given...

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Bibliographic Details
Main Author: Apostolov, Apostol
Language:ENG
Published: Université de Strasbourg 2012
Subjects:
Online Access:http://tel.archives-ouvertes.fr/tel-00923158
http://tel.archives-ouvertes.fr/docs/00/92/31/58/PDF/Apostolov_Apostol_2012_ED414.pdf