IDH1/2 (isocitrate dehydrogenase 1/2) Mutations in Gliomas : Genotype-Phenotype Correlation, Prognostic impact, and Response to Irradiation
Since Parsons et al. (2008) found the frequent mutations of IDH1 (12%) in GBMs, various reports have studied the prevalence and characteristic of IDH1 and IDH2 mutations.The mutations in the isocitrate dehydrogenase 1 (IDH1) gene occur in nearly 40% of gliomas. The frequency of IDH1 mutations are in...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
Université Paris Sud - Paris XI
2012
|
| Subjects: | |
| Online Access: | http://tel.archives-ouvertes.fr/tel-00996458 http://tel.archives-ouvertes.fr/docs/00/99/64/58/PDF/VA_WANG_-_XiaoWei_26072012.pdf |