Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT cell stimulation : role of suppressive macrophages
INKT cells are non-conventional T lymphocytes that are restricted to glycolipid presenting CD1d molecule. iNKT cells express an invariant TCR a chain (Va14-Ja18 in mice and Va28-Ja18 in humans). Their particularity is to rapidly produce copious amounts of cytokines (IFN-? and IL-4) after activation...
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| Language: | English |
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Université René Descartes - Paris V
2013
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| Online Access: | http://tel.archives-ouvertes.fr/tel-01071267 http://tel.archives-ouvertes.fr/docs/01/07/12/67/PDF/va_Ghazarian_Liana.pdf |