Comparative Susceptibility and Mechanisms of Resistance to Host Defense Peptides in Daptomycin-Susceptible and Non-Susceptible Clinical Isolates of <em>Staphylococcus aureus</em>

Host defense peptides (HDPs) provide innate immune defense against invasive S. aureus infection. Recent studies suggest potential cross-resistance between HDPs and the lipopeptide antibiotic, daptomycin (DAP). Isolates that exhibit DAP non-susceptible phenotypes may have virulence advantages and pos...

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Bibliographic Details
Main Author: Johnson, Colin Wolcott
Format: Others
Published: Scholarship @ Claremont 2016
Subjects:
Online Access:http://scholarship.claremont.edu/cmc_theses/1303
http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=2348&amp;context=cmc_theses