Constructing Phylogenetic Trees Using Maximum Likelihood

Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tr...

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Main Author: Cho, Anna
Format: Others
Published: Scholarship @ Claremont 2012
Subjects:
Online Access:http://scholarship.claremont.edu/scripps_theses/46
http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1047&context=scripps_theses
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spelling ndltd-CLAREMONT-oai-scholarship.claremont.edu-scripps_theses-10472013-06-12T03:03:26Z Constructing Phylogenetic Trees Using Maximum Likelihood Cho, Anna Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tree is also determined using base substitution probabilities and conditional likelihoods. Felsenstein [2] introduced this method of finding an estimate for the maximum likelihood phylogenetic tree. We will explore this method in detail in this paper. 2012-04-09T07:00:00Z text application/pdf http://scholarship.claremont.edu/scripps_theses/46 http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1047&context=scripps_theses © 2012 Anna Cho Scripps Senior Theses Scholarship @ Claremont computational biology markov processes probability statistics Other Applied Mathematics
collection NDLTD
format Others
sources NDLTD
topic computational biology
markov processes
probability
statistics
Other Applied Mathematics
spellingShingle computational biology
markov processes
probability
statistics
Other Applied Mathematics
Cho, Anna
Constructing Phylogenetic Trees Using Maximum Likelihood
description Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tree is also determined using base substitution probabilities and conditional likelihoods. Felsenstein [2] introduced this method of finding an estimate for the maximum likelihood phylogenetic tree. We will explore this method in detail in this paper.
author Cho, Anna
author_facet Cho, Anna
author_sort Cho, Anna
title Constructing Phylogenetic Trees Using Maximum Likelihood
title_short Constructing Phylogenetic Trees Using Maximum Likelihood
title_full Constructing Phylogenetic Trees Using Maximum Likelihood
title_fullStr Constructing Phylogenetic Trees Using Maximum Likelihood
title_full_unstemmed Constructing Phylogenetic Trees Using Maximum Likelihood
title_sort constructing phylogenetic trees using maximum likelihood
publisher Scholarship @ Claremont
publishDate 2012
url http://scholarship.claremont.edu/scripps_theses/46
http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1047&context=scripps_theses
work_keys_str_mv AT choanna constructingphylogenetictreesusingmaximumlikelihood
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