Constructing Phylogenetic Trees Using Maximum Likelihood
Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tr...
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ndltd-CLAREMONT-oai-scholarship.claremont.edu-scripps_theses-10472013-06-12T03:03:26Z Constructing Phylogenetic Trees Using Maximum Likelihood Cho, Anna Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tree is also determined using base substitution probabilities and conditional likelihoods. Felsenstein [2] introduced this method of finding an estimate for the maximum likelihood phylogenetic tree. We will explore this method in detail in this paper. 2012-04-09T07:00:00Z text application/pdf http://scholarship.claremont.edu/scripps_theses/46 http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1047&context=scripps_theses © 2012 Anna Cho Scripps Senior Theses Scholarship @ Claremont computational biology markov processes probability statistics Other Applied Mathematics |
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computational biology markov processes probability statistics Other Applied Mathematics |
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computational biology markov processes probability statistics Other Applied Mathematics Cho, Anna Constructing Phylogenetic Trees Using Maximum Likelihood |
description |
Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tree is also determined using base substitution probabilities and conditional likelihoods. Felsenstein [2] introduced this method of finding an estimate for the maximum likelihood phylogenetic tree. We will explore this method in detail in this paper. |
author |
Cho, Anna |
author_facet |
Cho, Anna |
author_sort |
Cho, Anna |
title |
Constructing Phylogenetic Trees Using Maximum Likelihood |
title_short |
Constructing Phylogenetic Trees Using Maximum Likelihood |
title_full |
Constructing Phylogenetic Trees Using Maximum Likelihood |
title_fullStr |
Constructing Phylogenetic Trees Using Maximum Likelihood |
title_full_unstemmed |
Constructing Phylogenetic Trees Using Maximum Likelihood |
title_sort |
constructing phylogenetic trees using maximum likelihood |
publisher |
Scholarship @ Claremont |
publishDate |
2012 |
url |
http://scholarship.claremont.edu/scripps_theses/46 http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1047&context=scripps_theses |
work_keys_str_mv |
AT choanna constructingphylogenetictreesusingmaximumlikelihood |
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1716588764053110784 |