Synthesis of 2’ Modified Primers to Characterize Extension Events by Mutant Taq DNA Polymerases

Oligonucleotides enable many biotechnological applications; however they are easily degraded by nucleases. Many nucleotides modified at the 2’ position are degraded at decreased rates which improves oligonucleotide utility. Most applications of oligonucleotides rely on enzymatic synthesis. Unfortuna...

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Bibliographic Details
Main Author: Jackson, Constanza
Format: Others
Published: Scholarship @ Claremont 2015
Subjects:
Online Access:http://scholarship.claremont.edu/scripps_theses/592
http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1544&context=scripps_theses