Regulation des Reduced Folate Carrier (RFC1) in HPCT-1E3-Ratten-Hepatocytoma-Zellen durch Cytochrom P450-Induktoren vom Phenobarbital-Typ
The sodium dependent reduced folate carrier (Rfc1; Slc19a1) provides the major route for cellular uptake of antifolate chemotherapeutic drugs such as methotrexate (MTX) and reduced folates into liver, kidneys and other tissues. Despite its essential role in cancer treatment and for the body’s folate...
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Format: | Doctoral Thesis |
Language: | German |
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2006
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Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-34397 https://ul.qucosa.de/id/qucosa%3A10647 https://ul.qucosa.de/api/qucosa%3A10647/attachment/ATT-0/ |