The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis

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Background Histone methylation is thought to be central to the epigenetic mechanisms that maintain and confine cellular identity in multi-cellular organisms. To examine epigenetic roles in cellular homeostasis, we conditionally mutated the histone 3 lysine 4 methyltransferase, Mll2, in embryonic ste...

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Bibliographic Details
Main Authors: Stewart, A. Francis, Glaser, Stefan, Lubitz, Sandra, Loveland, Kate L., Ohbo, Kazu, Robb, Lorraine, Schwenk, Frieder, Seibler, Jost, Roellig, Daniela, Kranz, Andrea, Anastassiadis, Konstantinos
Format: Article
Language:English
Published: BioMed Central 2009
Subjects:
epigenetische Modifikationen
multi-cellular organisms
info:eu-repo/classification/ddc/610
ddc:610
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