Enzyme-catalysed regio- and enantioselective preparative scale synthesis of (S)-2-hydroxy alkanones
α-Hydroxy alkanones were synthesised with high enantiomeric purity by stereoselective enzyme-catalysed diketone reduction. Both diketone reduction and cofactor regeneration were accomplished with purified carbonyl reductase from Candida parapsilosis (CPCR2). The reaction products were isolated by co...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2015
|
| Subjects: | |
| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-188786 https://tud.qucosa.de/id/qucosa%3A29050 https://tud.qucosa.de/api/qucosa%3A29050/attachment/ATT-0/ |