Design of Multi-Stable Nucleic Acid Sequences

RNA molecules that can fold into two or more predefined alternative metastable structures can be designed rationally. We outline an algorithm for this task that reduces the problem to vertex coloring the union of all prescribed outerplanar secondary structure graphs. Starting from an ear decompositi...

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Bibliographic Details
Main Authors: Abfalter, Ingrid G., Flamm, Christoph, Stadler, Peter F.
Language:English
Published: Farin 2003
Subjects:
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa2-318448
https://ul.qucosa.de/id/qucosa%3A31844
https://ul.qucosa.de/api/qucosa%3A31844/attachment/ATT-0/