Abnormal Localization and Accumulation of FLT3-ITD, a Mutant Receptor Tyrosine Kinase Involved in Leukemogenesis

Abnormal Localization and Accumulation of FLT3-ITD, a Mutant Receptor Tyrosine Kinase Involved in Leukemogenesis

Aberrant subcellular localization of mutant transmembrane receptors is increasingly acknowledged as a possible mechanism for an altered signaling quality leading to transformation. There is evidence that mutated receptor tyrosine kinases of subclass III, for example the platelet-derived growth facto...

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Bibliographic Details
Main Authors: Koch, Sina, Jacobi, Angela, Ryser, Martin, Ehninger, Gerhard, Thiede, Christian
Other Authors: Karger,
Format: Article
Language:English
Published: Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden 2014
Subjects:
subzelluläre Lokalisierung
FLT3-ITD
Rezeptortyrosinkinase
akute myeloische Leukämie
Acute myeloid leukemia
Receptor tyrosine kinase
Subcellular localization
ddc:610
rvk:XA 10000
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-136167
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-136167
http://www.qucosa.de/fileadmin/data/qucosa/documents/13616/CTO20081881_2225.PDF

Internet

http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-136167
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-136167
http://www.qucosa.de/fileadmin/data/qucosa/documents/13616/CTO20081881_2225.PDF

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