Protein Binding Site Similarities as Driver for Drug Repositioning
Drug repositioning applies existing drugs to new disease indications. A prerequisite for drug repurposing is drug promiscuity - a drug's ability to bind to several targets, possibly leading to side effects on the other hand. One reason for drug promiscuity is binding site similarity between (ot...
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| Format: | Doctoral Thesis |
| Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2014
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| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-144517 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-144517 http://www.qucosa.de/fileadmin/data/qucosa/documents/14451/dissertation_joachim_haupt.pdf |