Enzyme-catalysed regio- and enantioselective preparative scale synthesis of (S)-2-hydroxy alkanones
α-Hydroxy alkanones were synthesised with high enantiomeric purity by stereoselective enzyme-catalysed diketone reduction. Both diketone reduction and cofactor regeneration were accomplished with purified carbonyl reductase from Candida parapsilosis (CPCR2). The reaction products were isolated by co...
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| Format: | Article |
| Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2015
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| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-188786 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-188786 http://www.qucosa.de/fileadmin/data/qucosa/documents/18878/c5ra02975a.pdf |