The effects and regulation of the Wnt inhibitor Dickkopf-1 and the mechanistic target of rapamycin in osteotropic cancers

As solid tumor types, breast and prostate cancer are rivalled only by lung cancer in their propensity to metastasize to bone in the later stages of disease. At advanced stages of disease, approximately 80% of breast and 90% of prostate cancer patients will present with bone metastases. Bone metastas...

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Bibliographic Details
Main Author: Browne, Andrew
Other Authors: Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus
Format: Doctoral Thesis
Language:English
Published: Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden 2017
Subjects:
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-228981
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-228981
http://www.qucosa.de/fileadmin/data/qucosa/documents/22898/AB_Thesis_FINAL_pdfa.pdf