Discovery of a novel form of Hedgehog that systemically circulates, and its signaling implications in Drosophila.
Hedgehog (Hh) shape up development by playing important role in signaling, and thereby controlling growth and pattern formation. It is for this reason that their spatial distribution is tightly regulated. The 19kDa active form of Hh is modified with a palmitate at its N-terminal and with cholesterol...
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| Format: | Doctoral Thesis |
| Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2011
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| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-64956 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-64956 http://www.qucosa.de/fileadmin/data/qucosa/documents/6495/TheThesis.pdf |