Resveratrol Differentially Regulates NAMPT and SIRT1 in Hepatocarcinoma Cells and Primary Human Hepatocytes

Resveratrol is reported to possess chemotherapeutic properties in several cancers. In this study, we wanted to investigate the molecular mechanisms of resveratrol-induced cell cycle arrest and apoptosis as well as the impact of resveratrol on NAMPT and SIRT1 protein function and asked whether there...

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Bibliographic Details
Main Authors: Schuster, Susanne, Garten, Antje
Other Authors: Universität Leipzig, Center for Pediatric Research Leipzig, University Hospital for Children and Adolescents
Format: Article
Language:English
Published: Universitätsbibliothek Leipzig 2014
Subjects:
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-142581
http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-142581
http://www.qucosa.de/fileadmin/data/qucosa/documents/14258/journal.pone.0091045.pdf