Genome Informatics for High-Throughput Sequencing Data Analysis

This thesis introduces three different algorithmical and statistical strategies for the analysis of high-throughput sequencing data. First, we introduce a heuristic method based on enhanced suffix arrays to map short sequences to larger reference genomes. The algorithm builds on the idea of an error...

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Bibliographic Details
Main Author: Hoffmann, Steve
Other Authors: Universität Leipzig, Fakultät für Mathematik und Informatik
Format: Doctoral Thesis
Language:English
Published: Universitätsbibliothek Leipzig 2014
Subjects:
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-152643
http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-152643
http://www.qucosa.de/fileadmin/data/qucosa/documents/15264/ThesisCVCat.pdf