Loss of Bace1 in mice does not alter the severity of caerulein induced pancreatitis

Context: Beta-site alpha-amyloid protein cleaving enzyme1 (BACE1) plays a key role in the pathogenesis of Alzheimer’s disease. Additional to its moderate expression in the brain, high levels of BACE1 mRNA were found in the pancreas. Murine Bace1 has been immunohistochemicaly detected at the apical p...

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Bibliographic Details
Main Authors: Heindl, Mario, Tuennemann, Jan, Sommerer, Ines, Mössner, Joachim, Hoffmeister, Albrecht
Other Authors: Universitätsklinikum Leipzig, Department für Innere Medizin, Neurologie und Dermatologie
Format: Article
Language:English
Published: Universitätsbibliothek Leipzig 2015
Subjects:
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-170593
http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-170593
http://www.qucosa.de/fileadmin/data/qucosa/documents/17059/OAP-2015-088-Hoffmeister.pone.0125556.pdf