The NAMPT-mediated NAD salvage pathway in cancer cell metabolism and its regulation by resveratrol

Nicotinamide adenine dinucleotide (NAD) is a key regulator of several metabolic and signaling pathways that are relevant in cancer cell survival. Cancer cells have an increased energy demand associated with an increased NAD turnover. Nicotinamide phosphoribosyltransferase (NAMPT), a key enzyme of th...

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Bibliographic Details
Main Author: Schuster, Susanne
Other Authors: Universität Leipzig, Fakultät für Biowissenschaften, Pharmazie und Psychologie
Format: Doctoral Thesis
Language:English
Published: Universitätsbibliothek Leipzig 2015
Subjects:
NAD
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-173401
http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-173401
http://www.qucosa.de/fileadmin/data/qucosa/documents/17340/Diss_Susi_150326_final3%2BUrheberKapitel1_BIBO2.pdf