Unraveling Phosphatidylinositol 4-kinase function in the yeast Golgi-endosomal system
In Saccharomyces cerevisiae, experiments with temperature-sensitive mutants of the PI4-kinase Pik1p revealed that the PI4P pool generated by this enzyme is essential for Golgi morphology and normal secretory function and that the PI4P pool at the Golgi represents a regulatory signal on its own. In o...
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Format: | Doctoral Thesis |
Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2005
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Online Access: | http://nbn-resolving.de/urn:nbn:de:swb:14-1126694538661-76719 http://nbn-resolving.de/urn:nbn:de:swb:14-1126694538661-76719 http://www.qucosa.de/fileadmin/data/qucosa/documents/1361/1126694538661-7671.pdf |