The Role of Secreted Frizzled Related Protein 3 (SFRP3) and the Wnt Signaling Pathway in PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma

<p>Rhabdomyosarcoma is the most common pediatric soft tissue sarcoma and demonstrates features of skeletal muscle. Of the two predominant (pediatric) subtypes, embryonal (eRMS) and alveolar (aRMS), aRMS has the poorer prognosis, with a 5-year survival rate of <50%. The majority of aRMS tumo...

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Bibliographic Details
Main Author: Kephart, Julie Grondin
Other Authors: Linardic, Corinne M
Published: 2015
Subjects:
Wnt
Online Access:http://hdl.handle.net/10161/10503