The Design and Synthesis of Novel Chiral Z-Nitrones with Applications Towards the Syntheses of Enantiomerically Pure 4-Hydroxy Amino Acids
<p>A number of 4-hydroxy amino acids have been synthesized via 1,3-dipolar cycloadditions of novel Z-nitrones and substituted olefins. Three achiral nitrones were synthesized in pursuit of a conformationally stable yet reactive Z-nitrone. The carboisopropoxynitrone was determined to be the be...
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2009
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| Online Access: | http://hdl.handle.net/10161/3201 |