Regulation of Tcra/Tcrd Locus Conformation during Thymocyte Development

<p>The chromatin architecture of antigen receptor loci has been hypothesized to facilitate the assembly of variable (V), diversity (D), and joining (J) gene segments during lymphocyte development. The 1.6 megabase Tcra/Tcrd locus is unique since it undergoes highly divergent Tcrd and Tcra rec...

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Bibliographic Details
Main Author: Shih, Han-Yu
Other Authors: Krangel, Michael
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10161/5548